Coronavirus disease 2019 (COVID-19)

Definition

Coronavirus disease 2019 (COVID-19) is a respiratory illness that causes fever, coughing, and shortness of breath, but many other symptoms can occur. COVID-19 is caused by a highly infectious virus. Most people get mild to moderate illness. Older adults and people with certain health conditions are at high risk for severe illness and death. More than one million people in the United States have died from COVID-19.

Alternative Names

Coronavirus - 2019; Coronavirus - novel 2019; 2019 Novel coronavirus; SARS-CoV-2

Causes

COVID-19 is caused by the SARS-CoV-2 virus (severe acute respiratory syndrome coronavirus 2). Coronaviruses are a family of viruses that can affect people and animals. They can cause mild to moderate respiratory illnesses, such as the common cold. Some coronaviruses can cause severe illness that can lead to pneumonia and even death.

COVID-19 most readily spreads to people within close contact (about 6 feet or 2 meters). When someone with the illness coughs, sneezes, sings, talks, or breathes, droplets and very small particles spray into the air. You can catch the illness if you breathe in these droplets or particles or they land on your eyes, nose, or mouth.

In some instances, COVID-19 may spread through the air and infect people who are more than 6 feet away. Small droplets and particles can remain in the air for minutes to hours. This is called airborne (or aerosol) transmission, and it occurs especially in enclosed spaces with poor ventilation. However, it is more common for COVID-19 to spread through close contact.

Less often, the illness can spread if you touch a surface with the virus on it, and then touch your eyes, nose, mouth, or face. But this is thought to be a much less common way in which the virus spreads.

COVID-19 can spread from person to person quickly. As the virus spreads, it can change, and new variants of the virus will occur. Different variants may spread more quickly or be more resistant to treatments or vaccines. Taking steps to slow the spread of the virus, such as by getting a COVID-19 vaccine, can help slow the development of new variants.

While the United States Federal COVID-19 Public Health Emergency has ended, COVID-19 is still a health concern, in particular for people at high risk of serious illness.

Symptoms

COVID-19 symptoms range from mild to severe. Older people and people with certain existing health conditions have a higher risk of developing severe illness and death. Health conditions that increase this risk include:

Symptoms of COVID-19 may include:

This is not a complete list of possible symptoms. Symptoms may change with new variants of the virus.

Some people may have no symptoms at all. Many people have some, but not all of these symptoms. Symptoms can also vary, depending on whether you are vaccinated and boosted.

Symptoms may appear within 2 to 14 days after being exposed. Most often, symptoms appear around 5 days after exposure. However, you can spread the virus even when you do not have symptoms.

More severe symptoms that require seeking medical help right away include:

Exams and Tests

If you have symptoms of COVID-19, you can perform a self-test. Your health care provider also may decide to test you for the disease.

If you get tested for COVID-19, swabs from the back of the nose, the front of the nose, or the throat will be collected to test for SARS-CoV-2.

Treatment

If you are recovering at home, supportive care is given to help relieve symptoms. People with severe illness will be treated in the hospital.

The types of medicines given may vary depending upon how sick you are, your risk factors for serious illness from the disease, your age, and possibly what variant of the virus is causing the infection.

If you test positive for COVID-19, your provider may recommend antiviral medicines.

If given soon after you become infected (5 to 7 days, depending on the medicine), these medicines help your immune system fight off the virus. They may be given to adults and children with mild to moderate illness who are not hospitalized. These medicines include:

If you are being cared for in the hospital and are receiving oxygen therapy, treatment for COVID-19 may include the following medicines:

Based on available evidence, current treatment guidelines from the National Institutes of Health recommend against using some drugs for COVID-19, including chloroquine, hydroxychloroquine, and ivermectin. Do not take any drugs to treat COVID-19 except those prescribed by your provider. Check with your provider before treating yourself or a loved one with vitamins, nutrients, or any medicines prescribed in the past for other health problems. Since some COVID-19 medicines have interactions with other medicines or supplements you may be taking, always check with your provider before starting them.

Possible Complications

Complications can include:

When to Contact a Medical Professional

You should contact your provider:

Call 911 or the local emergency number if you have:

Prevention

You can take steps to protect yourself and others from COVID-19:

References

Centers for Disease Control and Prevention website. COVID-19: COVID-19 treatments and medications. www.cdc.gov/coronavirus/2019-ncov/your-health/treatments-for-severe-illness.html. Updated January 18, 2024. March 13, 2024.

Centers for Disease Control and Prevention website. COVID-19: Frequently asked questions about COVID-19 vaccination. www.cdc.gov/coronavirus/2019-ncov/vaccines/faq.html. Updated October 4, 2023. Accessed March 13, 2024.

Centers for Disease Control and Prevention website. Long COVID or post-COVID conditions. www.cdc.gov/coronavirus/2019-ncov/long-term-effects/index.html. Updated July 20, 2023. Accessed September 19, 2023.

Centers for Disease Control and Prevention website. Respiratory virus guidance. www.cdc.gov/respiratory-viruses/guidance/respiratory-virus-guidance.html. Updated March 1, 2024. Accessed March 5, 2024.

Centers for Disease Control and Prevention website. Stay up to date with COVID-19 vaccines. www.cdc.gov/coronavirus/2019-ncov/vaccines/stay-up-to-date.html#children. Updated March 7, 2024. Accessed March 13, 2024.

Centers for Disease Control and Prevention website. Variants. www.cdc.gov/coronavirus/2019-ncov/variants/index.html. Updated February 6, 2023. Accessed March 13, 2024.

National Institutes of Health. COVID-19 treatment guidelines. Clinical management of adults summary. www.covid19treatmentguidelines.nih.gov/management/clinical-management-of-adults/clinical-management-of-adults-summary/. Updated February 29, 2024. Accessed March 13, 2024.


Review Date: 2/22/2023
Reviewed By: Frank D. Brodkey, MD, FCCM, Associate Professor, Section of Pulmonary and Critical Care Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team. Editorial update 03/13/2024.
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