Muscle atrophy is the wasting (thinning) or loss of muscle tissue.
Muscle wasting; Wasting; Atrophy of the muscles
There are three types of muscle atrophy: physiologic, pathologic, and neurogenic.
Physiologic atrophy is caused by not using the muscles enough. This type of atrophy can often be reversed with exercise and better nutrition. People who are most affected are those who:
Pathologic atrophy is seen with aging, starvation, and diseases such as Cushing disease (because of taking too much medicines called corticosteroids).
Neurogenic atrophy is the most severe type of muscle atrophy. It can be from an injury to, or disease of a nerve that connects to the muscle. This type of muscle atrophy tends to occur more suddenly than physiologic atrophy.
Examples of diseases affecting the nerves that control muscles:
Although people can adapt to muscle atrophy, even minor muscle atrophy causes some loss of movement or strength.
Other causes of muscle atrophy may include:
An exercise program may help treat muscle atrophy. Exercises may include ones done in a swimming pool to reduce the muscle workload, and other types of rehabilitation. Your health care provider can tell you more about this.
People who cannot actively move one or more joints can do exercises using braces or splints.
Contact your provider for an appointment if you have unexplained or long-term muscle loss. You can often see this when you compare one hand, arm, or leg to the other.
The provider will perform a physical examination and ask about your medical history and symptoms, including:
The provider will look at your arms and legs and measure muscle size. This may help determine which nerves are affected.
Tests that may be performed include:
Treatment may include physical therapy, ultrasound therapy and, in some cases, surgery to correct a contracture.
Ball JW, Dains JE, Flynn JA, Solomon BS, Stewart RW. Musculoskeletal system. In: Ball JW, Dains JE, Flynn JA, Solomon BS, Stewart RW, eds. Seidel's Guide to Physical Examination. 10th ed. St Louis, MO: Elsevier; 2023:chap 22.
Selcen D. Muscle diseases. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 393.
Reviewed By: Joseph V. Campellone, MD, Department of Neurology, Cooper Medical School at Rowan University, Camden, NJ. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.