Bilirubin is a yellowish pigment found in bile, which is a fluid produced by the liver and stored in the gallbladder.
This article is about a lab test to measure the amount of bilirubin in the urine. Large amounts of bilirubin in the body can lead to jaundice.
Bilirubin may also be measured with a blood test.
Conjugated bilirubin - urine; Direct bilirubin - urine
This test can be done on any urine sample.
For an infant, thoroughly wash the area where urine exits the body.
This procedure may take a few tries. An active baby can move the bag, causing urine to go into the diaper.
Check the infant often and change the bag after the infant has urinated into it. Drain the urine from the bag into the container provided by your health care provider.
Deliver the sample to the laboratory or to your provider as soon as possible.
Many medicines can interfere with blood test results.
The test involves only normal urination, and there is no discomfort.
This test may be done to diagnose liver or gallbladder problems.
Bilirubin is not normally found in the urine.
Increased levels of bilirubin in the urine may be due to:
Bilirubin can break down in light. That is why babies with jaundice are sometimes placed under blue fluorescent lamps.
Dean AJ, Lee DC. Bedside laboratory and microbiologic procedures. In: Roberts JR, Custalow CB, Thomsen TW, eds. Roberts and Hedges' Clinical Procedures in Emergency Medicine and Acute Care. 7th ed. Philadelphia, PA: Elsevier; 2019:chap 67.
Korenblat KM, Berk PD. Approach to the patient with jaundice or abnormal liver test results. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 138.
Riley RS, McPherson RA. Basic examination of urine. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 24th ed. Philadelphia, PA: Elsevier; 2022:chap 29.
Reviewed By: David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine, Seattle, WA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.