The PTH test measures the level of parathyroid hormone in the blood.
PTH stands for parathyroid hormone. It is a protein hormone released by the parathyroid gland.
A laboratory test can be done to measure the amount of PTH in your blood.
Parathormone; Parathormone (PTH) intact molecule; Intact PTH; Hyperparathyroidism - PTH blood test; Hypoparathyroidism - PTH blood test
A blood sample is needed.
Ask your health care provider if you should stop eating or drinking for some period of time before the test. Most often, you will not need to fast or stop drinking.
When the needle is inserted to draw blood, some people feel moderate pain. Others feel only a prick or stinging. Afterward, there may be some throbbing or slight bruising. This soon goes away.
PTH is released by the parathyroid glands. The 4 small parathyroid glands are located in the neck, near or attached to the back side of the thyroid gland. The thyroid gland is located in the neck, just above where your collarbones meet in the middle.
PTH controls calcium, phosphorus, and vitamin D levels in the blood. It is important for regulating bone growth. Your provider may order this test if:
To help understand whether your PTH is normal, your provider will measure your blood calcium at the same time.
Normal values are 10 to 55 picograms per milliliter (pg/mL).
Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or test different specimens. Talk to your provider about the meaning of your specific test results. Try to go back to the same lab each time you need to have your PTH level tested so your provider can reliably compare your results over time.
A PTH value in the normal range can still be inappropriate when serum calcium levels are high. Talk to your provider about what your result means.
A higher-than-normal level may occur with:
A lower-than-normal level may occur with:
Other conditions for which the test may be ordered include:
There is little risk involved with having your blood taken. Veins and arteries vary in size from one person to another and from one side of the body to the other. Taking blood from some people may be more difficult than from others.
Other risks associated with having blood drawn are slight, but may include:
Bringhurst FR, Demay MB, Kronenberg HM. Hormones and disorders of mineral metabolism. In: Melmed S, Auchus RJ, Goldfine AB, Koenig RJ, Rosen CJ, eds. Williams Textbook of Endocrinology. 14th ed. Philadelphia, PA: Elsevier; 2020:chap 29.
Klemm KM, Klein MJ, Zhang Y. Biochemical markers of bone metabolism. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 24th ed. Philadelphia, PA: Elsevier; 2022:chap 16.
Reviewed By: Robert Hurd, MD, Professor of Endocrinology and Health Care Ethics, Xavier University, Cincinnati, OH. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.